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FIB-4 scores were calculated annually for each patient, and the highest score determined each patients categorization into low-, indeterminate-, or high-risk groups based on established age-specific cutoffs

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Specifically, TLR4 and TLR5 in the intestine recognize specific components of the gut microbiota (GM) and contribute to the immune defense mechanism against the influenza virus during this process (146)

The findings indicated that SRC3-Exo treatment significantly reduced neuronal ferroptosis and inhibited the activation of microglia and astrocytes